John A McCauley Selected Research

HCV NS3-4A Protease Inhibitors

10/2016	Hepatitis C virus NS3/4a protease inhibitors.
8/2012	MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.
1/2010	MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease.

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John A McCauley Research Topics

Disease

6	Infections 01/2020 - 01/2010
3	Hyperalgesia 07/2007 - 02/2003
2	Parkinson Disease (Parkinson's Disease) 01/2017 - 01/2016
2	Body Weight (Weight, Body) 08/2012 - 01/2010
2	Hepatitis C 04/2008 - 01/2008
2	Pain (Aches) 07/2007 - 02/2003
1	Malaria 01/2020
1	Disease Progression 01/2017
1	Major Depressive Disorder (Major Depressive Disorders) 12/2015
1	Chronic Hepatitis C 08/2012
1	Virus Diseases (Viral Diseases) 08/2012

Drug/Important Bio-Agent (IBA)

3	HCV NS3-4A Protease InhibitorsIBA 10/2016 - 01/2010
3	CarrageenanIBA 07/2007 - 02/2003
2	Phosphotransferases (Kinase)IBA 01/2017 - 01/2016
2	elbasvirIBA 03/2014 - 12/2013
2	grazoprevirIBA 03/2014 - 08/2012
2	InterferonsIBA 12/2013 - 08/2012
2	Peptide Hydrolases (Proteases)FDA Link 04/2008 - 01/2008
1	artemisinIBA 01/2020
1	Antimalarials (Antimalarial Agents)IBA 01/2020
1	plasmepsin (plasmepsin I)IBA 01/2020
1	Leucine (L-Leucine)FDA Link 01/2016
1	N-Methylaspartate (NMDA)IBA 12/2015
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2015
1	Protease Inhibitors (Protease Inhibitor)IBA 03/2014
1	indoleIBA 12/2013
1	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 08/2012
1	telaprevirIBA 08/2012
1	Ribavirin (Virazole)FDA LinkGeneric 08/2012
1	Antiviral Agents (Antivirals)IBA 01/2010
1	vaniprevirIBA 01/2010
1	benzimidazoleIBA 04/2004

Therapy/Procedure

4	Therapeutics 01/2020 - 01/2010
1	Oral Administration 01/2020